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The STEP 4 follow-up confirmed that weight regain occurs after discontinuation, establishing that obesity, like other chronic diseases, requires ongoing treatment for sustained benefit

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Zepbound (tirzepatide) is a prescription medication approved by the FDA for chronic weight management in adults with obesity (BMI 30 kg/m) or overweight (BMI 27 kg/m) with at least one weight-related comorbid condition

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